TYSABRI® (natalizumab) is a treatment approved for relapsing forms of MS in the United States and relapsing-remitting MS in the European Union...TYSABRI was recently approved in the U.S. to induce and maintain clinical response and remission in adult patients with moderately to severely active Crohn's disease (CD) with evidence of inflammation who have had an inadequate response to, or are unable to tolerate, conventional CD therapies and inhibitors of TNF-alpha.
I'd like to learn more about this drug called TYSABRI. It looks like it can help more than one disease! Multiple Sclerosis and Chron's Disease.
Did you read this part of the press release?
What we need are treatments that not going to cure you of one disease but kill you with another! You would think that in today's day and age they could come up with a drug that doesn't have a side effect of increasing INFECTION! Come on, that's like prescription drugs 101.
Is MS similar to Chron's Disease? Why is Tysabri being used for both diseases?
The more advanced the treatment, the more specialize the drug molecule. If you're looking for a panacea, keep looking. The drug companies would go out of business if they ever invented a cure-all.
I'm not saying they give drugs side-effects on purpose. Sometimes the mechanism by which a molecule works causes a change in another pathway, which is what causes side affects. If the main action of the drug is greatly improved over previous generations of drugs, the side affects are simply deemed to be "worth it".
Well I have a close friend with MS and let me tell you, they would be more than willing to try this new drug, even with the risk of those side effects. There are many uncurable diseases out there so your choise is basically made for you: either slowly die from the disease, or give yourself a chance with a new drug.
And as far as Chron's: it won't kill you unless it's really bad, but Chron's is a quality of life issue, and if TYSABRI cures Chron's then I'm all for that, too.
How is TYSABRI even remotely considered beneficial if the side affects can be dangerous infections?
Chron's Disease is an auto-immune disease. Many Chron's treatments suppress the immune system... TYSABRI doesn't sound much different than the rest.
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